The Melquiades Project

an experiment in the precision of unconventional communication

179 notes &

Take Your Placebos, Or Die

jtotheizzoe:

In a trial of drugs for heart disease, one group who took their drugs regularly, as directed were 40% less likely to die than those who did not. 

The catch? Both of those groups were taking placebos. From NeuroSkeptic

What the placebo adherence effect demonstrates is that there may be confounds no-one has thought of. They might even be impossible to measure. And if these mystery confounds can literally kill you, they can probably cause all kinds of other effects too.

The patients were corrected for every health and lifestyle factor they could think of. So there must be a cause, we just have no freakin’ clue what it is.

Placebo effect, you win this time …

378 notes &

I’m in love with you, and I’m not in the business of denying myself the simple pleasure of saying true things. I’m in love with you, and I know that love is just a shout into the void, and that oblivion is inevitable, and that we’re all doomed and that there will come a day when all our labor has been returned to dust, and I know the sun will swallow the only earth we’ll ever have, and I am in love with you.
The Fault in Our Stars (via myreligioniskindness)

(via bonkersforpotter)

0 notes &

Ha Ha Tonka - Westward Bound

My room is overheated and faces the sun. On bright mornings during this noncommittal winter I wake up craving grapefruit with a soft sheen of sweat brought forth on the places on my thighs where the sunlight shines through the windows. So I get out of bed in the morning with otherwise dormant feelings from summer waking with me. Most of them are put right back to sleep as soon as I step outside, but if it’s sunny enough I can feel them still through squinting eyes and the buildings that begin to glow with the setting sun around 4pm. That’s when I bake, bake, bake, and listen to this song.

Filed under sun sunny Summer winter baking Ha Ha Tonka midwest

306 notes &

The joy of bourbon drinking is not the pharmacological effect of the C2H5OH on the cortex but rather the instant of the whiskey being knocked back and the little explosion of Kentucky U.S.A. sunshine in the cavity of the nasopharynx and the hot bosky bite of Tennessee summertime —aesthetic considerations to which the effect of the alcohol is, if not dispensable, at least secondary.

Walker Percy in “Bourbon, Neat,” quoted by Portrait of the Artist as a Young Man. Since I first read this essay, when I was perhaps fourteen or fifteen years old, I have remembered that invaluable phrase precisely and used it on occasion: “hot bosky bite.”

For some time, I supposed —stupidly— that Percy had simply invented the word “bosky” in an effort to capture the way bourbon tastes and feels: two syllables, because it is a matter-of-fact sort of flavor, concise even when complex. But of course “bosky” is a real word, with a definition: “Having abundant bushes, shrubs, or trees.”

Good God! If you’ve ever been in a hot Southern state in the summer, out away from the roads and houses, in fields or little glades surrounded by plain, unprepossessing woods, and if you’ve tasted bourbon, you must recognize that this is inspired, precise lyricism; it is the result of brilliant observation and masterful, unaffected diction. The flatness of bland blue skies which cling close to buzzing, sun-bleached, lush yet crackling lands, the simultaneity of heat and verdancy: this is the best metaphor I know for the flavor of bourbon, which, I regret, is irreplaceable if one gives up drinking.

Note also the two forms of prose: the specialized vocabulary of the scientist as a foil to the poetics of the the real point, the evocation of place and season and atmosphere. The sort of lexical pyrotechnics for which many esteem David Foster Wallace predates him, of course, although in “Oblivion” I believe he brought it to an apotheosis of sorts (an anti-apotheosis: the dull triumph of inhumanly technical language). But it is worth noting because Wallace’s real gifts, like Percy’s, have nothing to do with the niftiness of his interdisciplinary sentences; that is a matter of style, a style which either supports higher artistic aims or is lazy mannerism, as most writing in fact is.

(via mills)

(via jtotheizzoe)